Is There a Role for Intraoperative Neuromonitoring in Intradural Extramedullary Spine Tumors? Results and Indications from an Institutional Series

Manuela D’Ercole, Quintino Giorgio D’Alessandris, Michele Di Domenico, Benedetta Burattini, Grazia Menna, Alessandro Izzo, Filippo Maria Polli, Giuseppe Maria Della Pepa, Alessandro Olivi, Nicola Montano

Research output: Contribution to journalArticlepeer-review

Abstract

While intraoperative neurophysiological monitoring (IONM) is considered a standard for intramedullary spinal cord tumor surgery, the effective role of IONM in intradural extramedullary (IDEM) tumors is still debated. We present the results of 60 patients affected by IDEM tumors undergoing surgery with the aid of IONM. Each patient was evaluated according to the modified McCormick scale (MMS) at admission, discharge and at follow-up. During surgery, motor evoked potentials (MEPs) and somatosensory evoked potentials (SEPs) were studied using the Medtronic NIM-eclipse® 32-channel system (Medtronic Xomed, Inc. 6743 Southpoint Drive North Jacksonville FL USA). Patients’ age, gender and tumor location did not affect MMS modifications. Tumors involving more than three levels had an increased likelihood of MMS worsening, while meningioma pathology was associated with worse preoperative and 1-year follow-up MMS. No MEP amplitude ratio was able to predict clinical variations, while intraoperative SEP worsening was associated with 100% risk of poor MMS at discharge and with 50% risk of poor MMS at long-term follow-up. In our opinion, SEP monitoring is a valid tool that may contribute to the preservation of the patient’s neurological status. MEP monitoring is not mandatory in IDEM surgery while more studies are required to explore the feasibility and the role of D-wave in this kind of surgery.

Original languageEnglish (US)
Article number1103
JournalJournal of Personalized Medicine
Volume13
Issue number7
DOIs
StatePublished - Jul 2023
Externally publishedYes

Keywords

  • intradural extramedullary tumors
  • intraoperative neurophysiological monitoring
  • spinal tumors

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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