Abstract
Cerebrospinal fluid samples from controls and patients with multiple sclerosis (MS) were split and sent to laboratories with different experiences for the detection of Chlamydia pneumoniae by polymerase chain reaction. Vanderbilt investigators identified C. pneumoniae in the majority of patients with MS and uncommonly in controls. Laboratories at Johns Hopkins University, University of Umeå, and the Centers for Disease Control and Prevention did not identify C. pneumoniae in any of the samples. Conflicting reports of C. pneumoniae detection in the same samples from patients with MS highlight the need to exchange detection techniques among laboratories involved in this controversy.
Original language | English (US) |
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Pages (from-to) | 289-294 |
Number of pages | 6 |
Journal | Multiple Sclerosis |
Volume | 8 |
Issue number | 4 |
DOIs | |
State | Published - Jan 1 2002 |
Externally published | Yes |
Keywords
- Chlamydia pneumoniae
- Multiple sclerosis
- Polymerase chain reaction
ASJC Scopus subject areas
- Neurology
- Clinical Neurology