Is awareness of chronic kidney disease associated with evidence-based guideline-concordant outcomes?

Delphine S. Tuot, Laura C. Plantinga, Chi Yuan Hsu, Neil R. Powe

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Background: Awareness of chronic kidney disease (CKD) is low. Efforts are underway to increase recognition of CKD among patients, assuming that such an increase will lead to better outcomes through greater adherence to proven therapies. Few studies have tested this assumption. Methods: CKD awareness, defined by a 'yes' answer to 'Have you ever been told by a healthcare provider you have weak or failing kidneys?', was assessed among 2,404 adults with CKD stages 1-4, who participated in the 2003-2008 National Health and Nutrition Examination Surveys. Odds of blood pressure (BP) control, self-reported use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB), and glycemic control, were determined among those aware vs. unaware of their CKD. Results: Optimal BP control, ACEI/ARB use and glycemic control were low in the US adult population with CKD, although there was a recent increase in attainment of guideline-concordant BP control. Odds of BP control and ACEI/ARB use were not different among individuals aware of their CKD compared to those unaware (adjusted odds ratio (AOR) 0.91; 95% CI 0.52-1.58 and AOR 0.75; 0.44-1.30, respectively). CKD awareness among diabetic participants was not associated with glycemic control (AOR 0.41; 95% CI 0.14-1.18). Conclusion: Awareness of CKD is not associated with more optimal BP control, ACEI/ARB use or glycemic control. Future efforts in this area should further explore the measurement of CKD awareness and behaviors associated with CKD awareness.

Original languageEnglish (US)
Pages (from-to)191-197
Number of pages7
JournalAmerican Journal of Nephrology
Issue number2
StatePublished - Feb 2012
Externally publishedYes


  • Awareness
  • Chronic kidney disease
  • Guidelines
  • National Health And Nutrition Examination Survey (NHANES)

ASJC Scopus subject areas

  • Nephrology


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