Investigating femtosecond-laser-induced two-photon photoacoustic generation

Ben E. Urban, Ji Yi, Vladislav Yakovlev, Hao F. Zhang

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


We investigated two-photon absorption-based photoacoustic generation and compared it with corresponding photoluminescence emission. Experimental results revealed expected quadratic dependences on the incident optical fluence in both photoacoustic and photoluminescence processes. We also investigated the influence of optical scattering on the generation of two-photon photoacoustic and photoluminescence signals and found that photoacoustic signals attenuated more slowly than photoluminescence signals when the optical scattering coefficient was increased, which was attributed to a weaker ultrasonic attenuation than that the optical attenuation in the scattering medium. Finally, we showed three-dimensional two-photon photoacoustic imaging.

Original languageEnglish (US)
Article number085001
JournalJournal of biomedical optics
Issue number8
StatePublished - Aug 2014
Externally publishedYes


  • nonlinear optics.
  • photoacoustic effect
  • two-photon absorption

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering
  • Biomaterials


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