Inverted takotsubo cardiomyopathy and the fundamental diagnostic role of echocardiography

Arantza Manzanal, Lara Ruiz, Jose Madrazo, Majesh Makan, Julio Perez

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Takotsubo cardiomyopathy is characterized by the development of transient focal wall-motion abnormalities that involve the apical and midventricular segments, in the absence of obstructive coronary artery disease. A variant, inverted takotsubo cardiomyopathy, was described in 2010. We report 3 cases in which each patient's transthoracic echocardiogram revealed the characteristic basal and midventricular segmental akinesis of this variant. This pattern is not associated with coronary artery distribution, and it therefore can be differentiated from coronary artery disease with the use of echocardiography, by evaluating the distribution and temporal changes of akinetic areas.

Original languageEnglish (US)
Pages (from-to)56-59
Number of pages4
JournalTexas Heart Institute Journal
Issue number1
StatePublished - 2013
Externally publishedYes


  • Cardiomyopathies/diagnosis/physiopathology
  • Echocardiography
  • Left/diagnosis
  • Takotsubo cardiomyopathy/diagnosis
  • Ventricular dysfunction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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