Abstract
The most common procedure for isolating genes that predispose to a certain disease is positional cloning. This process is initiated by mapping the responsible gene to its location on a chromosome linked to the disease. Successive cloning of the region results in the isolation of candidate genes. Finally, identification of mutations by mutational analysis points to the correct gene.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 116-118 |
| Number of pages | 3 |
| Journal | Clinical and Experimental Allergy, Supplement |
| Volume | 25 |
| Issue number | 2 |
| State | Published - 1995 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Fingerprint
Dive into the research topics of 'Introduction to positional cloning'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS