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Intrathecal baclofen therapy and the treatment of spasticity

Research output: Contribution to journalArticlepeer-review

Abstract

This monograph discusses the current treatment of spasticity via intrathecal baclofen (ITB) therapy. It describes the pathophysiology and the primary anatomic substrate of spasticity, and the current modern surgical and pharmacologic treatment options. Baclofen pumps are discussed in detail, including their implantation procedure, and basic modes of operation and design. Complications of ITB treatment are examined including infection, pump failure, and baclofen overdosing and withdrawal issues. Results from a recent cost-analysis study of ITB therapy are included, and promising future trends in the treatment of spasticity.

Original languageEnglish (US)
Pages (from-to)185-192
Number of pages8
JournalNeurosurgery Quarterly
Volume17
Issue number3
DOIs
StatePublished - Sep 2007

Keywords

  • Baclofen pump
  • Intrathecal baclofen therapy
  • Spasticity

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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