Intramolecular Nitrile Oxide Cycloaddition (INOC) Reactions in the Indole Series. 2. Total Synthesis of Racemic and Optically Active Paliclavine and 5-epi-Paliclavine

Alan P. Kozikowski, Yon Yih Chen

Research output: Contribution to journalLetterpeer-review

116 Scopus citations

Abstract

The first total synthesis of the ergot alkaloid paliclavine and the formal total synthesis of paspaclavine in optically active form are described.

Original languageEnglish (US)
Pages (from-to)5248-5250
Number of pages3
JournalJournal of Organic Chemistry
Volume46
Issue number25
DOIs
StatePublished - Dec 1981
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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