Intracranial leiomyosarcoma in a patient with AIDS

H. G. Brown, P. C. Burger, A. Olivi, A. K. Sills, P. A. Barditch-Crovo, R. R. Lee

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


We report an intracranial leiomyosarcoma in the pontine cistern of a 34-year-old woman infected with the human immunodeficiency virus (HIV). The clinical, radiological and pathological data are reviewed. The tumor was Epstein-Barr virus (EBV) positive by in situ hybridization. This case emphasizes that smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection may have a role in development of these tumors.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
Issue number1
StatePublished - Jan 1999


  • Brain, neoplasms
  • Human Immunodeficiency Virus
  • Leiomyosarcoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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