Intra-aneurysmal flow reductions in a thin film nitinol flow diverter

Youngjae Chun, Soojung Claire Hur, Colin P. Kealey, Daniel S. Levi, K. P. Mohanchandra, Dino Di Carlo, Jeff D. Eldredge, Fernando Vinuela, Gregory P. Carman

Research output: Contribution to journalArticlepeer-review


A novel hyper-elastic thin film nitinol (HE-TFN) covered stent has been developed to promote aneurysm occlusion by diminishing flow in the aneurysm. Laboratory aneurysm models were used to assess the flow changes produced by stents covered with different patterns of HE-TFN placed across the aneurysm neck in the parent vessel. The flow diverters were constructed by covering Wingspan stents (Boston Scientific) with different HE-TFNs (i.e., of 82% and 77% porosity) and deployed in both invitro wide-neck and fusiform glass aneurysm models. In wide-neck aneurysms, the 82% porous HE-TFN stent reduced mean flow velocity in the middle of the sac by 86 1%, while the 77% porous stent reduced the velocity by 93 5% (n = 3). Local wall shear rates were also significantly reduced by about 98% in this model after device placement. Tests conducted on the fusiform aneurysm revealed smaller intra-aneurysmal flow velocity reduction by 48 3% for the 82% porous stent and by 59 7% for the 77% porous stent. The wall shear was reduced by approximately 50% by HE-TFN stents in fusiform models. These results suggest that HE-TFN covered stents have the potential to promote thrombosis in both wide-neck and fusiform aneurysm sacs.

Original languageEnglish (US)
Article number055021
JournalSmart Materials and Structures
Issue number5
StatePublished - May 2011
Externally publishedYes

ASJC Scopus subject areas

  • Signal Processing
  • Civil and Structural Engineering
  • Atomic and Molecular Physics, and Optics
  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Electrical and Electronic Engineering


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