Interventional Therapies for Pain in Cancer Patients: a Narrative Review

David Hao, Shawn Sidharthan, Juan Cotte, Mary Decker, Mariam Salisu-Orhurhu, Dare Olatoye, Jay Karri, Jonathan M. Hagedorn, Peju Adekoya, Charles Odonkor, Amitabh Gulati, Vwaire Orhurhu

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: Pain is a prevalent symptom in the lives of patients with cancer. In light of the ongoing opioid epidemic and increasing awareness of the potential for opioid abuse and addiction, clinicians are progressively turning to interventional therapies. This article reviews the interventional techniques available to mitigate the debilitating effects that untreated or poorly treated pain have in this population. Recent Findings: A range of interventional therapies and technical approaches are available for the treatment of cancer-related pain. Many of the techniques described may offer effective analgesia with less systemic toxicity and dependency than first- and second-line oral and parenteral agents. Neuromodulatory techniques including dorsal root ganglion stimulation and peripheral nerve stimulation are increasingly finding roles in the management of oncologic pain. Summary: The goal of this pragmatic narrative review is to discuss interventional approaches to cancer-related pain and the potential of such therapies to improve the quality of life of cancer patients.

Original languageEnglish (US)
Article number44
JournalCurrent pain and headache reports
Issue number7
StatePublished - Jul 2021


  • Cancer pain
  • Interventional pain management
  • Musculoskeletal pain
  • Neuromodulation
  • Quality of life
  • Spine-related pain
  • Visceral pain

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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