Abstract
To evaluate the reliability of Chlamydia pneumoniae-specific immunoglobulin G (IgG) and IgA antibody titers as measured by the microimmunofluorescence (MIF) test, we compared results from 392 individuals using a standard MIF protocol at two academic laboratories. The kappas for dichotomous titers (≥16 versus <16) were 0.39 for IgA and 0.53 for IgG. Measurement error likely attenuates C. pneumoniae-disease associations; the magnitude of attenuation can be estimated from results of studies such as this one.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 615-617 |
| Number of pages | 3 |
| Journal | Clinical and Diagnostic Laboratory Immunology |
| Volume | 11 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2004 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Clinical Biochemistry
- Microbiology (medical)