Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-γ-induced upregulation of B7-H1 (CD274)

Keyphrases

• Interferon-α (IFN-α) 100%
• Constitutive Expression 100%
• IRF1 100%
• B7-H1 100%
• CD274 100%
• B7-H1 Expression 60%
• Cancer Cells 40%
• Molecular Mechanism 20%
• In Cancer 20%
• Transcriptional Repressor 20%
• Cancer-related 20%
• Tumor Immunity 20%
• Small Interfering RNA (siRNA) 20%
• Signal Transducer 20%
• Immune Surveillance 20%
• Knockdown 20%
• Host Immune Response 20%
• A549 Cells 20%
• Site-directed mutagenesis 20%
• Induced Expression 20%
• Human Lung Cancer Cell Line 20%
• Electrophoretic Mobility Shift Assay 20%
• Transcription Inhibitors 20%
• AG490 20%
• Luciferase Assay 20%
• Translational Start Site 20%
• Co-inhibitory Molecules 20%
• Janus-activated Kinase 20%

Immunology and Microbiology

• interferon 100%
• Upregulation 100%
• Interferon Regulatory Factor 1 100%
• Cancer Cell 40%
• Promoter Region 20%
• Immunosurveillance 20%
• Site Directed Mutagenesis 20%
• Gel Mobility Shift Assay 20%
• Tumor Immunity 20%
• Lung Cancer Cell Line 20%