TY - JOUR
T1 - Integration of structure, function and mass transport in the myocardium
AU - Zinemanas, D.
AU - Beyar, R.
AU - Sideman, S.
AU - Arts, T.
AU - Ter Keurs, H. E D J
AU - Bassingthwaighte, J.
AU - Lanir, Y.
PY - 1995
Y1 - 1995
N2 - A left ventricular (LV) model that integrates muscle mechanics, coronary flow, and fluid transport, and accounts for the three-phase (fiber-blood- interstitium) myocardial structure and composition, is used to study the interactions between the mechanics, coronary flow and fluid and mass transport in the myocardium. Theoretical simulations elucidate the effects of ventricular load, coronary perfusion pressure, and fluid and mass transport on ventricular performance and coronary dynamics. The analysis yields a direct relation between cardiac function and structure to cardiac mechanics, coronary flow, and intramyocardial fluid (and mass) transport, and allows to study the interactions between coronary flow, ventricular and myocardial mechanics and intramyocardial fluid shifts.
AB - A left ventricular (LV) model that integrates muscle mechanics, coronary flow, and fluid transport, and accounts for the three-phase (fiber-blood- interstitium) myocardial structure and composition, is used to study the interactions between the mechanics, coronary flow and fluid and mass transport in the myocardium. Theoretical simulations elucidate the effects of ventricular load, coronary perfusion pressure, and fluid and mass transport on ventricular performance and coronary dynamics. The analysis yields a direct relation between cardiac function and structure to cardiac mechanics, coronary flow, and intramyocardial fluid (and mass) transport, and allows to study the interactions between coronary flow, ventricular and myocardial mechanics and intramyocardial fluid shifts.
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M3 - Article
C2 - 8540405
AN - SCOPUS:0029116590
SN - 0065-2598
VL - 382
SP - 279
EP - 292
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
ER -