Integrated concentrations of growth hormone correlated with plasma testosterone and bone age in preadolescent and adolescent males

R. G. Thompson; A. Rodriguez; A. Kowarski; C. J. Migeon; R. M. Blizzard

doi:10.1210/jcem-35-2-334

Integrated concentrations of growth hormone correlated with plasma testosterone and bone age in preadolescent and adolescent males

R. G. Thompson, A. Rodriguez, A. Kowarski, C. J. Migeon, R. M. Blizzard

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

The integrated concentration of growth hormone (ICGH) was studied in 17 normal preadolescent and adolescent boys and 16 normal adult males. The ICGH was determined over a 16-24 hour period under normal ambulatory conditions without the use of exogenous stimuli. The mean ± SD ICGH of 5.6 ± 3. 6 ng/ml for the boys is significantly higher than the mean of 1. 8 ± 1.0 for adult males. There is not an increase in ICGH associated with increase in bone age, progression of puberty, or increase in plasma testosterone. ICGH is markedly elevated in some boys prior to onset of puberty or elevation of plasma testosterone. This is in contrast to earlier reports that both exogenous and endogenous androgens may stimulate the growth hormone response to arginine and/or insulininduced hypoglycemia.

Original language	English (US)
Pages (from-to)	334-337
Number of pages	4
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	35
Issue number	2
DOIs	https://doi.org/10.1210/jcem-35-2-334
State	Published - 1972
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

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10.1210/jcem-35-2-334

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title = "Integrated concentrations of growth hormone correlated with plasma testosterone and bone age in preadolescent and adolescent males",

abstract = "The integrated concentration of growth hormone (ICGH) was studied in 17 normal preadolescent and adolescent boys and 16 normal adult males. The ICGH was determined over a 16-24 hour period under normal ambulatory conditions without the use of exogenous stimuli. The mean ± SD ICGH of 5.6 ± 3. 6 ng/ml for the boys is significantly higher than the mean of 1. 8 ± 1.0 for adult males. There is not an increase in ICGH associated with increase in bone age, progression of puberty, or increase in plasma testosterone. ICGH is markedly elevated in some boys prior to onset of puberty or elevation of plasma testosterone. This is in contrast to earlier reports that both exogenous and endogenous androgens may stimulate the growth hormone response to arginine and/or insulininduced hypoglycemia.",

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T1 - Integrated concentrations of growth hormone correlated with plasma testosterone and bone age in preadolescent and adolescent males

AU - Thompson, R. G.

AU - Rodriguez, A.

AU - Kowarski, A.

AU - Migeon, C. J.

AU - Blizzard, R. M.

PY - 1972

Y1 - 1972

N2 - The integrated concentration of growth hormone (ICGH) was studied in 17 normal preadolescent and adolescent boys and 16 normal adult males. The ICGH was determined over a 16-24 hour period under normal ambulatory conditions without the use of exogenous stimuli. The mean ± SD ICGH of 5.6 ± 3. 6 ng/ml for the boys is significantly higher than the mean of 1. 8 ± 1.0 for adult males. There is not an increase in ICGH associated with increase in bone age, progression of puberty, or increase in plasma testosterone. ICGH is markedly elevated in some boys prior to onset of puberty or elevation of plasma testosterone. This is in contrast to earlier reports that both exogenous and endogenous androgens may stimulate the growth hormone response to arginine and/or insulininduced hypoglycemia.

AB - The integrated concentration of growth hormone (ICGH) was studied in 17 normal preadolescent and adolescent boys and 16 normal adult males. The ICGH was determined over a 16-24 hour period under normal ambulatory conditions without the use of exogenous stimuli. The mean ± SD ICGH of 5.6 ± 3. 6 ng/ml for the boys is significantly higher than the mean of 1. 8 ± 1.0 for adult males. There is not an increase in ICGH associated with increase in bone age, progression of puberty, or increase in plasma testosterone. ICGH is markedly elevated in some boys prior to onset of puberty or elevation of plasma testosterone. This is in contrast to earlier reports that both exogenous and endogenous androgens may stimulate the growth hormone response to arginine and/or insulininduced hypoglycemia.

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Integrated concentrations of growth hormone correlated with plasma testosterone and bone age in preadolescent and adolescent males

Abstract

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