Insights into the endoscopic management of esophageal achalasia

Elizabeth Brindise; Mouen A. Khashab; Rami El Abiad

doi:10.1177/26317745211014706

Insights into the endoscopic management of esophageal achalasia

Elizabeth Brindise, Mouen A. Khashab, Rami El Abiad

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Achalasia is a primary esophageal motility disorder characterized by the loss of inhibitory neurons in the myenteric plexus, resulting in impaired relaxation of the esophagogastric junction. Achalasia is an incurable disease, and the treatment modalities are aimed at disruption of the esophagogastric junction and vary widely from pharmacological to endoscopic to surgical. Traditional endoscopic therapy includes pneumatic dilation, botulinum toxin injection, and peroral endoscopic myotomy. This review aims to provide an overview of the endoscopic management of achalasia, while focusing on the utilization of peroral endoscopic myotomy and other novel approaches.

Original language	English (US)
Journal	Therapeutic Advances in Gastrointestinal Endoscopy
Volume	14
DOIs	https://doi.org/10.1177/26317745211014706
State	Published - 2021

Keywords

EndoFLIP
achalasia
peroral endoscopic myotomy

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.1177/26317745211014706

Cite this

@article{a136a951c52c41e6bdded037f48985b3,

title = "Insights into the endoscopic management of esophageal achalasia",

abstract = "Achalasia is a primary esophageal motility disorder characterized by the loss of inhibitory neurons in the myenteric plexus, resulting in impaired relaxation of the esophagogastric junction. Achalasia is an incurable disease, and the treatment modalities are aimed at disruption of the esophagogastric junction and vary widely from pharmacological to endoscopic to surgical. Traditional endoscopic therapy includes pneumatic dilation, botulinum toxin injection, and peroral endoscopic myotomy. This review aims to provide an overview of the endoscopic management of achalasia, while focusing on the utilization of peroral endoscopic myotomy and other novel approaches.",

keywords = "EndoFLIP, achalasia, peroral endoscopic myotomy",

author = "Elizabeth Brindise and Khashab, {Mouen A.} and {El Abiad}, Rami",

note = "Publisher Copyright: {\textcopyright} The Author(s), 2021.",

year = "2021",

doi = "10.1177/26317745211014706",

language = "English (US)",

volume = "14",

journal = "Therapeutic Advances in Gastrointestinal Endoscopy",

issn = "1179-5522",

publisher = "SAGE Publications Ltd",

}

TY - JOUR

T1 - Insights into the endoscopic management of esophageal achalasia

AU - Brindise, Elizabeth

AU - Khashab, Mouen A.

AU - El Abiad, Rami

N1 - Publisher Copyright: © The Author(s), 2021.

PY - 2021

Y1 - 2021

N2 - Achalasia is a primary esophageal motility disorder characterized by the loss of inhibitory neurons in the myenteric plexus, resulting in impaired relaxation of the esophagogastric junction. Achalasia is an incurable disease, and the treatment modalities are aimed at disruption of the esophagogastric junction and vary widely from pharmacological to endoscopic to surgical. Traditional endoscopic therapy includes pneumatic dilation, botulinum toxin injection, and peroral endoscopic myotomy. This review aims to provide an overview of the endoscopic management of achalasia, while focusing on the utilization of peroral endoscopic myotomy and other novel approaches.

AB - Achalasia is a primary esophageal motility disorder characterized by the loss of inhibitory neurons in the myenteric plexus, resulting in impaired relaxation of the esophagogastric junction. Achalasia is an incurable disease, and the treatment modalities are aimed at disruption of the esophagogastric junction and vary widely from pharmacological to endoscopic to surgical. Traditional endoscopic therapy includes pneumatic dilation, botulinum toxin injection, and peroral endoscopic myotomy. This review aims to provide an overview of the endoscopic management of achalasia, while focusing on the utilization of peroral endoscopic myotomy and other novel approaches.

KW - EndoFLIP

KW - achalasia

KW - peroral endoscopic myotomy

UR - http://www.scopus.com/inward/record.url?scp=85105455004&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85105455004&partnerID=8YFLogxK

U2 - 10.1177/26317745211014706

DO - 10.1177/26317745211014706

M3 - Review article

C2 - 34017943

AN - SCOPUS:85105455004

SN - 1179-5522

VL - 14

JO - Therapeutic Advances in Gastrointestinal Endoscopy

JF - Therapeutic Advances in Gastrointestinal Endoscopy

ER -

Insights into the endoscopic management of esophageal achalasia

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this