@article{a2ed55e5b92745f5b37b0837f87421b5,
title = "Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling",
abstract = "Chokshi et al. demonstrate that visual experience-induced expression of H1a and its interaction with mGluR5 selectively depress intracortical synapses in an NMDAR-dependent manner. Such metaplasticity may benefit in vivo circuit function by allowing input-specific homeostatic control.",
keywords = "H1a, NMDA receptor, mGluR5, metabotropic glutamate receptor, metaplasticity, visual cortex",
author = "Varun Chokshi and Ming Gao and Grier, {Bryce D.} and Ashley Owens and Hui Wang and Worley, {Paul F.} and Lee, {Hey Kyoung}",
note = "Funding Information: This work was supported by NIH grants R01-EY014882 (to H.-K.L.) and R01- DA010309 (to P.F.W.). The authors would like to thank Dr. Alfredo Kirkwood for helpful discussions on this project and Dr. Rejji Kuruvilla for help on qPCR experiments. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = nov,
day = "20",
doi = "10.1016/j.neuron.2019.08.017",
language = "English (US)",
volume = "104",
pages = "736--748.e6",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "4",
}