Infrasellar craniopharyngiomas: Case report and review of the literature

H. Deutsch, K. Kothbauer, M. Persky, F. J. Epstein, G. I. Jallo

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Although craniopharyngiomas account for a large percentage of pediatric intracranial tumors, there is a bimodal age distribution. Most of these neoplasms are suprasellar or sellar in location. In this report we describe an unusual case of an infrasellar craniopharyngioma in a child. Only four previous cases of infrasellar craniopharyngiomas with no sellar involvement have been described. Infrasellar craniopharyngiomas are part of the continuum representing intracranial craniopharyngiomas and ameloblastomas of the jaw. A transnasal endoscopic biopsy was performed with a preliminary diagnosis of craniopharyngioma. The patient then underwent a radical resection of the infrasellar tumor via a subfrontal transbasal approach. This case illustrates a rare and unusual location for a craniopharyngioma. Craniopharyngiomas should be considered in the differential diagnosis of infrasellar neoplasms. Infrasellar craniopharyngiomas compromise part of the spectrum of tumors originating from enamel-forming neural crest cells.

Original languageEnglish (US)
Pages (from-to)121-128
Number of pages8
JournalSkull Base
Issue number2
StatePublished - 2001
Externally publishedYes


  • Ameloblastoma
  • Craniopharyngioma
  • Infrasellar region
  • Nasopharynx
  • Rathke's pouch

ASJC Scopus subject areas

  • Clinical Neurology


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