Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a peltier-cooled sample stage

Christopher E. Von Seggern; Ben D. Gardner; Robert J. Cotter

doi:10.1021/ac049575v

Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a peltier-cooled sample stage

Christopher E. Von Seggern, Ben D. Gardner, Robert J. Cotter

School of Medicine

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Infrared atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used to analyze frozen samples generated using a Peltier-cooled sample stage. This allows for the analysis of samples in water without the addition of matrix, in near-native conditions, and with minimal loss of water due to evaporation. Analysis of frozen samples is extended to study peptides, carbohydrates, and glycolipids.

Original language	English (US)
Pages (from-to)	5887-5893
Number of pages	7
Journal	Analytical Chemistry
Volume	76
Issue number	19
DOIs	https://doi.org/10.1021/ac049575v
State	Published - Oct 1 2004

ASJC Scopus subject areas

Analytical Chemistry

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10.1021/ac049575v

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abstract = "Infrared atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used to analyze frozen samples generated using a Peltier-cooled sample stage. This allows for the analysis of samples in water without the addition of matrix, in near-native conditions, and with minimal loss of water due to evaporation. Analysis of frozen samples is extended to study peptides, carbohydrates, and glycolipids.",

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AB - Infrared atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used to analyze frozen samples generated using a Peltier-cooled sample stage. This allows for the analysis of samples in water without the addition of matrix, in near-native conditions, and with minimal loss of water due to evaporation. Analysis of frozen samples is extended to study peptides, carbohydrates, and glycolipids.

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Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a peltier-cooled sample stage

Abstract

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