Abstract
Analysis of 2778 primary and 606 regrafted cadaveric donor renal allograft recipients transplanted between June 1977 and July 1982 as part of the South-Eastern Organ Procurement Foundation (SEOPF) Prospective Study was performed to determine the influence ofchanges in presensitization on graft and patient outcome. Four mutually exclusive groups of patients were identified based on the relative difference in the percentage of panel-reactive antibody (PRA) from highest ever (peak) to most recent (current) pretransplant levels as follows: group 1 (unsensitized): peak = current PRA = 0; group 2 (rising or stable PRA): (peak = current PRA) >0; group 3 (small decrease): (peak - current PRA) = 1–40%) and group 4 (large decrease): (peak - current PRA)>40%. First-transplant recipients in group 4 had significantly higher mortality when comparedwith groups 1–3 (P40% had significantly lower overall graft survival (P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 124-129 |
| Number of pages | 6 |
| Journal | Transplantation |
| Volume | 38 |
| Issue number | 2 |
| State | Published - 1984 |
| Externally published | Yes |
ASJC Scopus subject areas
- Transplantation
- Immunology