Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life

Bryan S. Nelson; Camlin Tierney; Deborah Persaud; Jennifer Jao; Mark F. Cotton; Yvonne Bryson; Anne Coletti; Theodore D. Ruel; Stephen A. Spector; Christina Reding; Kira Bacon; Diane Costello; Charlotte Perlowski; Maria Leticia Santos Cruz; Josphat Kosgei; Sai Majji; Dwight E. Yin; Patrick Jean-Philippe; Ellen G. Chadwick

doi:10.1093/cid/ciac695

Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life

Bryan S. Nelson, Camlin Tierney, Deborah Persaud, Jennifer Jao, Mark F. Cotton, Yvonne Bryson, Anne Coletti, Theodore D. Ruel, Stephen A. Spector, Christina Reding, Kira Bacon, Diane Costello, Charlotte Perlowski, Maria Leticia Santos Cruz, Josphat Kosgei, Sai Majji, Dwight E. Yin, Patrick Jean-Philippe, Ellen G. Chadwick

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants.

Original language	English (US)
Pages (from-to)	E744-E747
Journal	Clinical Infectious Diseases
Volume	76
Issue number	3
DOIs	https://doi.org/10.1093/cid/ciac695
State	Published - Feb 1 2023

Keywords

CD4
HIV
Pneumocystis jirovecii pneumonia
cotrimoxazole
neonatal

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/ciac695

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Nelson, B. S., Tierney, C., Persaud, D., Jao, J., Cotton, M. F., Bryson, Y., Coletti, A., Ruel, T. D., Spector, S. A., Reding, C., Bacon, K., Costello, D., Perlowski, C., Santos Cruz, M. L., Kosgei, J., Majji, S., Yin, D. E., Jean-Philippe, P., & Chadwick, E. G. (2023). Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life. Clinical Infectious Diseases, 76(3), E744-E747. https://doi.org/10.1093/cid/ciac695

Nelson, BS, Tierney, C, Persaud, D, Jao, J, Cotton, MF, Bryson, Y, Coletti, A, Ruel, TD, Spector, SA, Reding, C, Bacon, K, Costello, D, Perlowski, C, Santos Cruz, ML, Kosgei, J, Majji, S, Yin, DE, Jean-Philippe, P & Chadwick, EG 2023, 'Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life', Clinical Infectious Diseases, vol. 76, no. 3, pp. E744-E747. https://doi.org/10.1093/cid/ciac695

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abstract = "We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants.",

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AU - Ruel, Theodore D.

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Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life

Abstract

Keywords

ASJC Scopus subject areas

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