Infants Receiving a Single Dose of Nirsevimab to Prevent RSV Do Not Have Evidence of Enhanced Disease in Their Second RSV Season

MELODY Study Group

Research output: Contribution to journalArticlepeer-review

Abstract

To characterize nirsevimab in the prevention of RSV, children from the Phase 3 MELODY trial were followed through their second RSV season. No increase in medically attended RSV lower respiratory tract infections or evidence of antibody-dependent enhancement of infection or disease severity was found for nirsevimab vs placebo recipients.

Original languageEnglish (US)
Pages (from-to)144-147
Number of pages4
JournalJournal of the Pediatric Infectious Diseases Society
Volume13
Issue number2
DOIs
StatePublished - Feb 1 2024

Keywords

  • immunization
  • monoclonal antibody
  • nirsevimab
  • respiratory syncytial virus

ASJC Scopus subject areas

  • General Medicine

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