Induction of TFEB promotes Kupffer cell survival and reduces lipid accumulation in MASLD

Keyphrases

• Metabolic 100%
• Kupffer Cells 100%
• Liver Disease 100%
• Cell Survival 100%
• Lipid Accumulation 100%
• Transcription Factor EB 100%
• Cell Death 25%
• Beneficial Effects 16%
• Macrophages 16%
• Lipid Stress 16%
• Liver Steatosis 16%
• Cell Fitness 16%
• Choline-deficient Diet 16%
• Liver 8%
• Disease Progression 8%
• Oxidative Stress 8%
• Liver Tissue 8%
• Disease Pathogenesis 8%
• Transgenic Mice 8%
• Lipids 8%
• Fibrosis 8%
• Lipid Metabolism 8%
• Cell Preservation 8%
• High-fat Diet 8%
• Master Regulator 8%
• Lipolysis 8%
• Filtration 8%
• Mitochondrial Fatty Acid Oxidation 8%
• High-sucrose 8%
• Diet Study 8%
• Hepatic Macrophages 8%
• High-sucrose Diet 8%
• Lysosome Function 8%
• Metabolic Liver Disease 8%
• Diet Model 8%
• Ferroptosis 8%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 8%
• Tissue Homeostasis 8%
• Tissue-resident Macrophages 8%

Biochemistry, Genetics and Molecular Biology

• Transcription Factors 100%
• Cell Survival 100%
• Lipid Storage 100%
• Kupffer Cell 100%
• Macrophage 33%
• Cell Death 25%
• Lipid 25%
• Sucrose 16%
• Choline 16%
• Oxidative Stress 8%
• Homeostasis 8%
• Lysosome 8%
• Lipid Metabolism 8%
• Transgenic Mouse 8%
• Beta Oxidation 8%
• Lipolysis 8%
• Ferroptosis 8%