Indicators of skin barrier integrity among newborns massaged with mustard oil in rural Nepal

A. Summers; M. O. Visscher; S. K. Khatry; J. B. Sherchand; S. C. LeClerq; J. Katz; J. M. Tielsch; L. C. Mullany

doi:10.1038/jp.2017.158

Indicators of skin barrier integrity among newborns massaged with mustard oil in rural Nepal

A. Summers, M. O. Visscher, S. K. Khatry, J. B. Sherchand, S. C. LeClerq, J. Katz, J. M. Tielsch, L. C. Mullany

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Objective:The objective of this study was to determine the skin barrier changes during postnatal month 1 among infants receiving routine mustard oil massage in the humid conditions of rural Nepal.Study Design:This was an observational study among 500 live-born neonates receiving mustard oil massage. Skin integrity such as erythema, rash, dryness, skin pH, stratum corneum protein concentration and transepidermal water loss was measured on days 1, 3, 7, 14 and 28.Results:Erythema and rash increased (worsened) during weeks 1 and 2, then decreased over weeks 3 and 4. Skin pH (6.1±0.5 to 5.0±0.6) and stratum corneum protein (16.6±7.9 to 13.5±5.9 μg cm -2) decreased. Transepidermal water loss increased from 33.2±23.5 to 43.0±24.5 g m -2 h -1 at day 28. Skin pH and stratum corneum protein were higher for early versus late premature infants.Conclusion:Premature and full-term skin condition was generally poor especially during the first 2 weeks, improving thereafter. Maturational changes were evident.

Original language	English (US)
Pages (from-to)	64-70
Number of pages	7
Journal	Journal of Perinatology
Volume	38
Issue number	1
DOIs	https://doi.org/10.1038/jp.2017.158
State	Published - Jan 1 2018

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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title = "Indicators of skin barrier integrity among newborns massaged with mustard oil in rural Nepal",

abstract = "Objective:The objective of this study was to determine the skin barrier changes during postnatal month 1 among infants receiving routine mustard oil massage in the humid conditions of rural Nepal.Study Design:This was an observational study among 500 live-born neonates receiving mustard oil massage. Skin integrity such as erythema, rash, dryness, skin pH, stratum corneum protein concentration and transepidermal water loss was measured on days 1, 3, 7, 14 and 28.Results:Erythema and rash increased (worsened) during weeks 1 and 2, then decreased over weeks 3 and 4. Skin pH (6.1±0.5 to 5.0±0.6) and stratum corneum protein (16.6±7.9 to 13.5±5.9 μg cm -2) decreased. Transepidermal water loss increased from 33.2±23.5 to 43.0±24.5 g m -2 h -1 at day 28. Skin pH and stratum corneum protein were higher for early versus late premature infants.Conclusion:Premature and full-term skin condition was generally poor especially during the first 2 weeks, improving thereafter. Maturational changes were evident.",

author = "A. Summers and Visscher, {M. O.} and Khatry, {S. K.} and Sherchand, {J. B.} and LeClerq, {S. C.} and J. Katz and Tielsch, {J. M.} and Mullany, {L. C.}",

note = "Funding Information: This study was supported by the National Institute for Child Health and Development (HD060712) and the Bill & Melinda Gates Foundation (OPP1084399). Publisher Copyright: {\textcopyright} 2018 Nature America, Inc., part of Springer Nature. All rights reserved.",

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AU - Visscher, M. O.

AU - Khatry, S. K.

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AU - LeClerq, S. C.

AU - Katz, J.

AU - Tielsch, J. M.

AU - Mullany, L. C.

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N2 - Objective:The objective of this study was to determine the skin barrier changes during postnatal month 1 among infants receiving routine mustard oil massage in the humid conditions of rural Nepal.Study Design:This was an observational study among 500 live-born neonates receiving mustard oil massage. Skin integrity such as erythema, rash, dryness, skin pH, stratum corneum protein concentration and transepidermal water loss was measured on days 1, 3, 7, 14 and 28.Results:Erythema and rash increased (worsened) during weeks 1 and 2, then decreased over weeks 3 and 4. Skin pH (6.1±0.5 to 5.0±0.6) and stratum corneum protein (16.6±7.9 to 13.5±5.9 μg cm -2) decreased. Transepidermal water loss increased from 33.2±23.5 to 43.0±24.5 g m -2 h -1 at day 28. Skin pH and stratum corneum protein were higher for early versus late premature infants.Conclusion:Premature and full-term skin condition was generally poor especially during the first 2 weeks, improving thereafter. Maturational changes were evident.

AB - Objective:The objective of this study was to determine the skin barrier changes during postnatal month 1 among infants receiving routine mustard oil massage in the humid conditions of rural Nepal.Study Design:This was an observational study among 500 live-born neonates receiving mustard oil massage. Skin integrity such as erythema, rash, dryness, skin pH, stratum corneum protein concentration and transepidermal water loss was measured on days 1, 3, 7, 14 and 28.Results:Erythema and rash increased (worsened) during weeks 1 and 2, then decreased over weeks 3 and 4. Skin pH (6.1±0.5 to 5.0±0.6) and stratum corneum protein (16.6±7.9 to 13.5±5.9 μg cm -2) decreased. Transepidermal water loss increased from 33.2±23.5 to 43.0±24.5 g m -2 h -1 at day 28. Skin pH and stratum corneum protein were higher for early versus late premature infants.Conclusion:Premature and full-term skin condition was generally poor especially during the first 2 weeks, improving thereafter. Maturational changes were evident.

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Indicators of skin barrier integrity among newborns massaged with mustard oil in rural Nepal

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