TY - GEN
T1 - Independent component imaging of disease signatures
AU - Wang, Yue
AU - Zhang, Junying
AU - Huang, Kun
AU - Khan, Javed
AU - Szabo, Zsolt
N1 - Publisher Copyright:
© 2002 IEEE.
PY - 2002
Y1 - 2002
N2 - This paper describes a neural computation approach to independent component imaging of disease signatures. The novel feature is to separate mixed imagery sources blindly over an informative index subspace. The recovery of patterns is achieved by independent component analysts, whose parameters are estimated using the infomax principle. We discuss the theoretic roadmap of the approach, and its applications to the partial volume correction in cDNA microarray expression and the neuro-transporter binding separation in positron emission tomography.
AB - This paper describes a neural computation approach to independent component imaging of disease signatures. The novel feature is to separate mixed imagery sources blindly over an informative index subspace. The recovery of patterns is achieved by independent component analysts, whose parameters are estimated using the infomax principle. We discuss the theoretic roadmap of the approach, and its applications to the partial volume correction in cDNA microarray expression and the neuro-transporter binding separation in positron emission tomography.
KW - Independent component analysis
KW - Microarrays
KW - Neural computation
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=84948679625&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948679625&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2002.1029293
DO - 10.1109/ISBI.2002.1029293
M3 - Conference contribution
AN - SCOPUS:84948679625
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 457
EP - 460
BT - 2002 IEEE International Symposium on Biomedical Imaging, ISBI 2002 - Proceedings
PB - IEEE Computer Society
T2 - IEEE International Symposium on Biomedical Imaging, ISBI 2002
Y2 - 7 July 2002 through 10 July 2002
ER -