Incidence, trends, and diagnosis of perioperative acute kidney injury

Justin M. Belcher, Chirag R. Parikh

Research output: Chapter in Book/Report/Conference proceedingChapter


The incidence of all postoperative acute kidney injury (AKI), including the subset requiring dialysis, is increasing. Modern definitions for AKI, including Risk, Injury, Failure, Loss, and End-Stage Kidney Disease (RIFLE), Acute Kidney Injury Network (AKIN), and Kidney Disease: Improving Global Outcomes (KDIGO), have increased sensitivity and have standardized understanding of AKI, allowing improved epidemiologic study. The reported incidence of AKI following cardiac surgery historically has varied by AKI definition from <1.5 % for cases requiring dialysis to 25 % when AKI is defined as a rise in creatinine of 25 %. AKI rates in noncardiac surgery are significantly lower with the exception of patients in the intensive care unit and those receiving solid organ transplants. Despite rising AKI incidence, multiple studies have found mortality rates in postoperative patients with AKI to either be stable or falling.

Original languageEnglish (US)
Title of host publicationPerioperative Kidney Injury
Subtitle of host publicationPrinciples of Risk Assessment, Diagnosis and Treatment
PublisherSpringer New York
Number of pages12
ISBN (Electronic)9781493912735
ISBN (Print)9781493912728
StatePublished - Jan 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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