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Incidence of influenza virus infection in early infancy: A prospective study in South Asia

  • Emily Henkle
  • , Mark C. Steinhoff
  • , Saad B. Omer
  • , Eliza Roy
  • , Shams E. Arifeen
  • , Rubhana Raqib
  • , Monica McNeal
  • , Robert F. Breiman
  • , William J. Moss
  • , K. Zaman

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.

Original languageEnglish (US)
Pages (from-to)170-173
Number of pages4
JournalPediatric Infectious Disease Journal
Volume30
Issue number2
DOIs
StatePublished - Feb 2011

Keywords

  • infants
  • influenza

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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