Incidence, location, and diagnostic evaluation of metastatic bone disease

William D. Hage, Albert J. Aboulafia, David M. Aboulafia

Research output: Contribution to journalArticlepeer-review


Metastatic carcinoma is the most common malignancy of bone. The clinical presentation of patients with skeletal metastasis is variable. When asked to evaluate a patient with a pathologic lesion or unexplained bone pain, the orthopedic surgeon should follow a logical sequence of steps in evaluating the patient with suspected metastasis to optimize care and avoid complications. In the majority of cases, a systematic approach to the patient with skeletal metastasis leads to the correct diagnosis.

Original languageEnglish (US)
Pages (from-to)515-528
Number of pages14
JournalOrthopedic Clinics of North America
Issue number4
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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