In vivo imaging of MSCs

Jeff W.M. Bulte

doi:10.1007/978-1-4614-5711-4_21

In vivo imaging of MSCs

Jeff W.M. Bulte

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Clinical applications of mesenchymal stromal/stem cells (MSCs) to treat a myriad of diseases are currently being initiated. For MSC therapy to become common practice, basic questions about the fate of MSCs once administered need to be addressed. These include the biodistribution, survival, and differentiation of MSCs. In this chapter, several imaging techniques are described that can be used to interrogate these questions in a clinically applicable manner, and several examples are discussed. Single-photon emission computed tomography (SPECT)/radioisotope imaging and magnetic resonance imaging (MRI) cell-tracking techniques are the two modalities that likely will become mainstays in clinical practice.

Original language	English (US)
Title of host publication	Mesenchymal Stromal Cells
Subtitle of host publication	Biology and Clinical Applications
Publisher	Springer New York
Pages	389-402
Number of pages	14
ISBN (Electronic)	9781461457114
ISBN (Print)	9781461457107
DOIs	https://doi.org/10.1007/978-1-4614-5711-4_21
State	Published - Jan 1 2013

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-1-4614-5711-4_21

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In vivo imaging of MSCs

Abstract

ASJC Scopus subject areas

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