In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

Rafat R. Ansari, Kwang I. Suh, Sparta J. Tumminia, Paul Russell, J. Samuel Zigler

Research output: Contribution to journalConference articlepeer-review

7 Scopus citations


A compact fiber optic probe developed by Ansari et al. for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain "cataractograms" in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained non-invasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.

Original languageEnglish (US)
Pages (from-to)202-210
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 1997
Externally publishedYes
EventProceedings of Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry and Endoscopy - San Remo, Italy
Duration: Sep 4 1997Sep 7 1997

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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