In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

Rafat R. Ansari; Kwang I. Suh; Sparta J. Tumminia; Paul Russell; J. Samuel Zigler

doi:10.1117/12.297843

In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

Rafat R. Ansari, Kwang I. Suh, Sparta J. Tumminia, Paul Russell, J. Samuel Zigler

Research output: Contribution to journal › Conference article › peer-review

7 Scopus citations

Abstract

A compact fiber optic probe developed by Ansari et al. for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain "cataractograms" in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained non-invasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.

Original language	English (US)
Pages (from-to)	202-210
Number of pages	9
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3192
DOIs	https://doi.org/10.1117/12.297843
State	Published - 1997
Externally published	Yes
Event	Proceedings of Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry and Endoscopy - San Remo, Italy Duration: Sep 4 1997 → Sep 7 1997

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Access to Document

10.1117/12.297843

Cite this

@article{c469fceb69f940c9a5a5e88dfbeea3e7,

title = "In-vivo {"}cataractograms{"} using a compact backscatter dynamic light scattering (DLS) probe",

abstract = "A compact fiber optic probe developed by Ansari et al. for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain {"}cataractograms{"} in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained non-invasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.",

author = "Ansari, {Rafat R.} and Suh, {Kwang I.} and Tumminia, {Sparta J.} and Paul Russell and {Samuel Zigler}, J.",

year = "1997",

doi = "10.1117/12.297843",

language = "English (US)",

volume = "3192",

pages = "202--210",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Proceedings of Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry and Endoscopy ; Conference date: 04-09-1997 Through 07-09-1997",

}

TY - JOUR

T1 - In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

AU - Ansari, Rafat R.

AU - Suh, Kwang I.

AU - Tumminia, Sparta J.

AU - Russell, Paul

AU - Samuel Zigler, J.

PY - 1997

Y1 - 1997

N2 - A compact fiber optic probe developed by Ansari et al. for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain "cataractograms" in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained non-invasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.

AB - A compact fiber optic probe developed by Ansari et al. for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain "cataractograms" in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained non-invasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.

UR - http://www.scopus.com/inward/record.url?scp=0031289513&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031289513&partnerID=8YFLogxK

U2 - 10.1117/12.297843

DO - 10.1117/12.297843

M3 - Conference article

AN - SCOPUS:0031289513

SN - 0277-786X

VL - 3192

SP - 202

EP - 210

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry and Endoscopy

Y2 - 4 September 1997 through 7 September 1997

ER -

In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this