In-vivo alignment comparing patient specific instrumentation with both conventional and computer assisted surgery (cas) instrumentation in total knee arthroplasty

Patient specific instrumentation (PSI) was developed to increase total knee arthroplasty (TKA) accuracy and efficiency. The study purpose was to compare immediate post-operative mechanical alignment, achieved using PSI, with conventional and computer assisted surgery (CAS) instruments in high volume TKA practices. This prospective, multicenter, non-randomized study accrued 66 TKA patients using PSI. A computed tomography (CT) based algorithm was used to develop the surgical plan. Sixty-two percent were females, 99% were diagnosed with osteoarthritis, average age at surgery was 66. years, and 33 was the average body mass index. A historical control group was utilized that underwent TKA using conventional instruments (n. =. 86) or CAS (n. =. 81), by the same set of surgeons. Postoperative mechanical alignment was comparable across the groups. Operative time mean and variance were significant.