In Vitro Assessment of Drug Activity Against Mycobacterium ulcerans

Oliver D. Komm, Deepak V. Almeida, Paul J. Converse, Eric L. Nuermberger

Research output: Chapter in Book/Report/Conference proceedingChapter


As acknowledged by the Clinical and Laboratory Standards Institute (CLSI), there is an insufficient evidence base on which to recommend a standard method for antimicrobial susceptibility testing against M. ulcerans. The agar proportion method has been recognized as the standard method for susceptibility testing against Mycobacterium tuberculosis complex (MTBC) isolates for decades (Woods GL, Engenack NL, Lin G, Turnidge JD (2018) CLSI standards: guidelines for health care excellence. Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic Actinomycetes, 3rd edn.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages6
StatePublished - 2022

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029


  • Agar proportion method
  • Buruli ulcer
  • In vitro susceptibility testing
  • Minimal inhibitory concentration (MIC)
  • Mycobacterium ulcerans

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology


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