In Vitro Assessment of Drug Activity Against Mycobacterium ulcerans

Oliver D. Komm; Deepak V. Almeida; Paul Converse; Eric L. Nuermberger

doi:10.1007/978-1-0716-1779-3_18

In Vitro Assessment of Drug Activity Against Mycobacterium ulcerans

Oliver D. Komm, Deepak V. Almeida, Paul Converse, Eric L. Nuermberger

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

As acknowledged by the Clinical and Laboratory Standards Institute (CLSI), there is an insufficient evidence base on which to recommend a standard method for antimicrobial susceptibility testing against M. ulcerans. The agar proportion method has been recognized as the standard method for susceptibility testing against Mycobacterium tuberculosis complex (MTBC) isolates for decades (Woods GL, Engenack NL, Lin G, Turnidge JD (2018) CLSI standards: guidelines for health care excellence. Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic Actinomycetes, 3rd edn.

Original language	English (US)
Title of host publication	Methods in Molecular Biology
Publisher	Humana Press Inc.
Pages	189-194
Number of pages	6
DOIs	https://doi.org/10.1007/978-1-0716-1779-3_18
State	Published - 2022

Publication series

Name	Methods in Molecular Biology
Volume	2387
ISSN (Print)	1064-3745
ISSN (Electronic)	1940-6029

Keywords

Agar proportion method
Buruli ulcer
In vitro susceptibility testing
Minimal inhibitory concentration (MIC)
Mycobacterium ulcerans

ASJC Scopus subject areas

Genetics
Molecular Biology

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10.1007/978-1-0716-1779-3_18

Cite this

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abstract = "As acknowledged by the Clinical and Laboratory Standards Institute (CLSI), there is an insufficient evidence base on which to recommend a standard method for antimicrobial susceptibility testing against M. ulcerans. The agar proportion method has been recognized as the standard method for susceptibility testing against Mycobacterium tuberculosis complex (MTBC) isolates for decades (Woods GL, Engenack NL, Lin G, Turnidge JD (2018) CLSI standards: guidelines for health care excellence. Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic Actinomycetes, 3rd edn.",

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AB - As acknowledged by the Clinical and Laboratory Standards Institute (CLSI), there is an insufficient evidence base on which to recommend a standard method for antimicrobial susceptibility testing against M. ulcerans. The agar proportion method has been recognized as the standard method for susceptibility testing against Mycobacterium tuberculosis complex (MTBC) isolates for decades (Woods GL, Engenack NL, Lin G, Turnidge JD (2018) CLSI standards: guidelines for health care excellence. Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic Actinomycetes, 3rd edn.

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In Vitro Assessment of Drug Activity Against Mycobacterium ulcerans

Abstract

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Keywords

ASJC Scopus subject areas

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