Extraembryonic membranes and fetal tissues were obtained from 55 specimens of 5-11 weeks conceptual age. The glucose-6-phosphate dehydrogenase (G6PD) elelctrophoretic phenotype was determined and correlated with that of maternal blood. Fifteen specimens were heterozygous for G6PD A, and for nine of these maternal allele could be dertermined. In none of these specimens did the isozyme pattern of the membraneous chorion or chorionic villi differ significantly from that of fetal tissue. We have obtained no evidence of non-random inactivation in extraembryonic membranes of human fetal specimens at this stage of development.
|Original language||English (US)|
|Number of pages||5|
|Journal||American journal of human genetics|
|State||Published - Dec 1 1979|
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