In a Pinch: Cefiderocol for CRAB Infections

Sara M. Karaba, Elizabeth B. Hirsch, Emily L. Heil

Research output: Contribution to journalArticlepeer-review

Abstract

Carbapenem-resistant Acinetobacter baumannii (CRAB) can cause significant infections with limited treatment options available. Falcone et al. (https://doi.org/ 10.1128/aac.02142-21) describe a single-center retrospective study comparing clinical outcomes among patients with CRAB infections treated with cefiderocol-containing versus colistin-containing regimens. Patients who received cefiderocol-containing regimens had lower 30-day mortality, though there are several limitations raised here, which make interpretation and applicability difficult.

Original languageEnglish (US)
JournalAntimicrobial agents and chemotherapy
Volume66
Issue number5
DOIs
StatePublished - May 2022

Keywords

  • Acinetobacter
  • CRAB
  • cefiderocol

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Pharmacology

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