Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study

Magnus O. Wijkman; Brian L. Claggett; Marcus V.B. Malachias; Muthiah Vaduganathan; Christie M. Ballantyne; Dalane W. Kitzman; Thomas Mosley; Kunihiro Matsushita; Scott D. Solomon; Marc A. Pfeffer

doi:10.1016/j.diabres.2022.110164

Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study

Magnus O. Wijkman
, Brian L. Claggett
, Marcus V.B. Malachias
, Muthiah Vaduganathan
, Christie M. Ballantyne
, Dalane W. Kitzman
, Thomas Mosley
, Kunihiro Matsushita
, Scott D. Solomon
, Marc A. Pfeffer

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

In this community-based cohort of 5861 individuals followed for median 7.2 years, the discriminatory ability of NT-proBNP alone in predicting mortality was similar to that of multiple conventional markers of risk in people without diabetes. In people with diabetes, NT-proBNP alone discriminated risk of mortality better than conventional risk factors.

Original language	English (US)
Article number	110164
Journal	Diabetes Research and Clinical Practice
Volume	194
DOIs	https://doi.org/10.1016/j.diabres.2022.110164
State	Published - Dec 2022

Keywords

B-type natriuretic peptide
Biomarkers
Diabetes mellitus
Epidemiology
Mortality
Risk prediction

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.diabres.2022.110164

Cite this

Wijkman, M. O., Claggett, B. L., Malachias, M. V. B., Vaduganathan, M., Ballantyne, C. M., Kitzman, D. W., Mosley, T., Matsushita, K., Solomon, S. D., & Pfeffer, M. A. (2022). Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study. Diabetes Research and Clinical Practice, 194, Article 110164. https://doi.org/10.1016/j.diabres.2022.110164

Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study. / Wijkman, Magnus O.; Claggett, Brian L.; Malachias, Marcus V.B. et al.
In: Diabetes Research and Clinical Practice, Vol. 194, 110164, 12.2022.

Research output: Contribution to journal › Article › peer-review

Wijkman, MO, Claggett, BL, Malachias, MVB, Vaduganathan, M, Ballantyne, CM, Kitzman, DW, Mosley, T, Matsushita, K, Solomon, SD & Pfeffer, MA 2022, 'Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study', Diabetes Research and Clinical Practice, vol. 194, 110164. https://doi.org/10.1016/j.diabres.2022.110164

Wijkman MO, Claggett BL, Malachias MVB, Vaduganathan M, Ballantyne CM, Kitzman DW et al. Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study. Diabetes Research and Clinical Practice. 2022 Dec;194:110164. doi: 10.1016/j.diabres.2022.110164

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abstract = "In this community-based cohort of 5861 individuals followed for median 7.2 years, the discriminatory ability of NT-proBNP alone in predicting mortality was similar to that of multiple conventional markers of risk in people without diabetes. In people with diabetes, NT-proBNP alone discriminated risk of mortality better than conventional risk factors.",

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AU - Wijkman, Magnus O.

AU - Claggett, Brian L.

AU - Malachias, Marcus V.B.

AU - Vaduganathan, Muthiah

AU - Ballantyne, Christie M.

AU - Kitzman, Dalane W.

AU - Mosley, Thomas

AU - Matsushita, Kunihiro

AU - Solomon, Scott D.

AU - Pfeffer, Marc A.

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KW - B-type natriuretic peptide

KW - Biomarkers

KW - Diabetes mellitus

KW - Epidemiology

KW - Mortality

KW - Risk prediction

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Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study

Abstract

Keywords

ASJC Scopus subject areas

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