Importance of bacterial growth phase in determining minimal bactericidal concentrations of penicillin and methicillin

K. S. Kim, B. F. Anthony

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The minimal inhibitory concentrations of penicillin against 96 strains of group B streptococci and of methicillin against 10 strains of Staphylococcus aureus were unrelated to the growth phase of test bacteria. However, the minimal bactericidal concentrations were significantly higher in the stationary phase than the logarithmic phase for both organisms (P<0.001 and <0.05, respectively).

Original languageEnglish (US)
Pages (from-to)1075-1077
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume19
Issue number6
DOIs
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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