Impaired renal function in progressive multiple sclerosis

P. A. Calabresi, H. Austin, M. K. Racke, A. Goodman, P. Choyke, H. Maloni, H. F. McFarland

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The authors analyzed renal function in 25 patients with progressive MS. The mean glomerular filtration rate (GFR) was 92 mL/min/1.73 m2, compared to the predicted GFR of 110 (p < 0.001). Nine of the 25 (36%) patients had abnormally low GFR (<90). The mean serum creatinine for patients with MS was lower than predicted normal values and poorly estimated GFR using standard equations. These data document impaired renal function in patients with progressive MS and have implications for treatment of these patients with potentially nephrotoxic drugs.

Original languageEnglish (US)
Pages (from-to)1799-1801
Number of pages3
Issue number11
StatePublished - Dec 10 2002
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology


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