Impaired metabolism in obstructive sleep apnea

Chenjuan Gu, Vsevolod Polotsky, Jonathan C. Jun

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Obstructive sleep apnea (OSA) is a common sleep disorder that often coexists with impaired metabolism. In this chapter, we focus on interactions between obesity, OSA and metabolic disorders, and treatment effects of OSA on metabolism. Specifically, we will discuss (1) pathogenic role of obesity and visceral obesity in developing OSA, (2) evidence showing that OSA impairs glucose and lipid metabolism independent of obesity, (3) treatment effects of OSA on metabolic outcomes from randomized controlled trials, and (4) clinical implications of these findings and future directions.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Sleep and Circadian Rhythms
Subtitle of host publicationVolume 1-6, Second Edition
PublisherElsevier
Pages278-288
Number of pages11
ISBN (Electronic)9780323910941
DOIs
StatePublished - Jan 1 2023

Keywords

  • Continuous positive airway pressure
  • Dyslipidemia
  • Insulin resistance
  • Obesity
  • Obstructive sleep apnea
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • General Neuroscience

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