Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

Tam Ly; Jyoti Gulia; Vasilios Pyrgos; Masashi Waga; Shmuel Shoham

Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

Tam Ly, Jyoti Gulia, Vasilios Pyrgos, Masashi Waga, Shmuel Shoham

Research output: Contribution to journal › Article › peer-review

Abstract

Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduced mortality (8% vs. 17%, p = 0.05), further antibiotic use (median -2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.

Original language	English (US)
Pages (from-to)	637-640
Number of pages	4
Journal	Therapeutics and Clinical Risk Management
Volume	4
Issue number	3
State	Published - 2008
Externally published	Yes

ASJC Scopus subject areas

Safety Research
Pharmacology, Toxicology and Pharmaceutics(all)
Pharmacology (medical)
Chemical Health and Safety

Cite this

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title = "Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time",

abstract = "Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduced mortality (8% vs. 17%, p = 0.05), further antibiotic use (median -2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.",

author = "Tam Ly and Jyoti Gulia and Vasilios Pyrgos and Masashi Waga and Shmuel Shoham",

year = "2008",

language = "English (US)",

volume = "4",

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T1 - Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

AU - Ly, Tam

AU - Gulia, Jyoti

AU - Pyrgos, Vasilios

AU - Waga, Masashi

AU - Shoham, Shmuel

PY - 2008

Y1 - 2008

N2 - Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduced mortality (8% vs. 17%, p = 0.05), further antibiotic use (median -2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.

AB - Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notification was associated with reduced mortality (8% vs. 17%, p = 0.05), further antibiotic use (median -2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.

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AN - SCOPUS:47849101414

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JO - Therapeutics and Clinical Risk Management

JF - Therapeutics and Clinical Risk Management

IS - 3

ER -

Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

Abstract

ASJC Scopus subject areas

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