Impact of trichiasis surgery on physical functioning in Ethiopian patients: Star trial

Meraf A. Wolle, Sandra D. Cassard, Emily W. Gower, Beatriz E. Munoz, Jiangxia Wang, Wondu Alemayehu, Sheila K. West

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Purpose To evaluate the physical functioning of Ethiopian trichiasis surgery patients before and 6 months after surgery. Design Nested cohort study. Methods This study was nested within the Surgery for Trichiasis, Antibiotics to Prevent Recurrence (STAR) clinical trial conducted in Ethiopia. Demographic information, ocular examinations, and physical functioning assessments were collected before and 6 months after surgery. A single score for patients' physical functioning was constructed using Rasch analysis. A multivariate linear regression model was used to determine if change in physical functioning was associated with change in visual acuity. Results Of the 438 participants, 411 (93.8%) had both baseline and follow-up questionnaires. Physical functioning scores at baseline ranged from -6.32 (great difficulty) to +6.01 (no difficulty). The percentage of participants reporting no difficulty in physical functioning increased by 32.6%; the proportion of participants in the mild/no visual impairment category increased by 8.6%. A multivariate linear regression model showed that for every line of vision gained, physical functioning improves significantly (0.09 units; 95% CI: 0.020.16). Conclusions Surgery to correct trichiasis appears to improve patients' physical functioning as measured at 6 months. More effort in promoting trichiasis surgery is essential, not only to prevent corneal blindness, but also to enable improved functioning in daily life.

Original languageEnglish (US)
Pages (from-to)850-857
Number of pages8
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - May 2011

ASJC Scopus subject areas

  • Ophthalmology


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