TY - JOUR
T1 - Impact of seafood and fruit consumption on bone mineral density
AU - Zalloua, Pierre A.
AU - Hsu, Yi Hsiang
AU - Terwedow, Henry
AU - Zang, Tonghua
AU - Wu, Di
AU - Tang, Genfu
AU - Li, Zhiping
AU - Hong, Xiumei
AU - Azar, Sami T.
AU - Wang, Binyan
AU - Bouxsein, Mary L.
AU - Brain, Joseph
AU - Cummings, Steven R.
AU - Rosen, Clifford J.
AU - Xu, Xiping
N1 - Funding Information:
This study is supported by the National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, grant R01 AR 045651. We are grateful for the assistance and cooperation of the faculty and staff of the Anhui Medical University Biomedical Institute, and we thank all study participants.
PY - 2007/1/20
Y1 - 2007/1/20
N2 - Objectives: Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, of BMD by using multiple regression models in a rural Chinese population. Methods: BMDs were measured at the hip and total body in 5848 men and 6207 women, aged 25-64. Dietary and supplemental intakes were assessed by a simple, one-page questionnaire tailored to collect nutritional information from large rural populations. Another questionnaire was used to collect information on the subjects' age, disease history, smoking, alcohol consumption, physical activity as well as women's menstrual status and reproductive history. Multiple regression models were used to assess the relationships among dietary variables and BMD, after adjusting for age, BMI (body mass index), weight, occupation, smoking status, and alcohol consumption. Results: Increasing seafood consumption was significantly associated with greater BMD in women (p < 0.001), especially those consuming more than 250 g per week of seafood. One thousand and three hundred and twenty-four men and 1479 women consumed >250 g of fruit per week. Higher fruit intake was found to be significantly associated with higher BMD in both sexes (p < 0.05). High vegetable consumption, however, did not positively impact BMD. Conclusions: This study with its large population size has identified preventive measures, as well as some risk factors, involved in bone loss and osteoporosis. Our results highlight the importance of several dietary variables as significant determinants of BMD. It also emphasizes the role of dietary intake in general and shows that specific foods, such as fruits and seafood, can positively impact BMD.
AB - Objectives: Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, of BMD by using multiple regression models in a rural Chinese population. Methods: BMDs were measured at the hip and total body in 5848 men and 6207 women, aged 25-64. Dietary and supplemental intakes were assessed by a simple, one-page questionnaire tailored to collect nutritional information from large rural populations. Another questionnaire was used to collect information on the subjects' age, disease history, smoking, alcohol consumption, physical activity as well as women's menstrual status and reproductive history. Multiple regression models were used to assess the relationships among dietary variables and BMD, after adjusting for age, BMI (body mass index), weight, occupation, smoking status, and alcohol consumption. Results: Increasing seafood consumption was significantly associated with greater BMD in women (p < 0.001), especially those consuming more than 250 g per week of seafood. One thousand and three hundred and twenty-four men and 1479 women consumed >250 g of fruit per week. Higher fruit intake was found to be significantly associated with higher BMD in both sexes (p < 0.05). High vegetable consumption, however, did not positively impact BMD. Conclusions: This study with its large population size has identified preventive measures, as well as some risk factors, involved in bone loss and osteoporosis. Our results highlight the importance of several dietary variables as significant determinants of BMD. It also emphasizes the role of dietary intake in general and shows that specific foods, such as fruits and seafood, can positively impact BMD.
KW - BMD
KW - Fruit
KW - Menopause
KW - Nutrition
KW - Osteoporosis
KW - Seafood
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U2 - 10.1016/j.maturitas.2006.05.001
DO - 10.1016/j.maturitas.2006.05.001
M3 - Article
C2 - 16806750
AN - SCOPUS:33845495859
SN - 0378-5122
VL - 56
SP - 1
EP - 11
JO - Maturitas
JF - Maturitas
IS - 1
ER -