Impact of phase of respiration on central venous catheter tip position

Patrick P. Pan, Bjorn I. Engstrom, Matthew P. Lungren, Danielle M. Seaman, Mark L. Lessne, Charles Y. Kim

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Purpose: To determine the impact of the phase of respiration on CVC tip position using cross-sectional imaging. Methods: We retrospectively analyzed the CT scans of 24 consecutive patients (eight men and 16 women, mean age 56.3 years, range 18-79) who underwent a CT scan protocol that includes both imaging of the thorax in inspiration and expiration. Only patients with a central venous catheter and absence of any substantial pulmonary pathology that might affect lung volumes were included. Measurements of the catheter tip location and central venous structures were obtained from inspiratory and expiratory phase images in each patient and compared using the paired t test. Results: The length of the SVC and superior mediastinum were significantly longer during inspiration compared to expiration (9 mm and 7 mm respectively, P<0.001 for both). The distance between the superior and inferior cavo-atrial junction did not change significantly with respiration. The catheter tip location moved on average 9 mm (range 0-25 mm) cephalad during inspiration compared to expiration (P=0.001) in relation to the superior cavoatrial junction. The amount of catheter tip movement correlated significantly with the degree of diaphragmatic excursion with respiration (R=0.58). During inspiration, the cavo-atrial junction was on average 11 mm inferior to the right cardiomediastinal angle observed on radiography, but was nearly identical during expiration (R=0.78, P<0.001). Conclusions: The central catheter tip position varied significantly with respiratory motion, with a mean excursion of 9 mm. The right cardiomediastinal border demonstrated a strong correlation with the actual location of the superior cavo-atrial junction in expiration, but not in inspiration.

Original languageEnglish (US)
Pages (from-to)383-387
Number of pages5
JournalJournal of Vascular Access
Issue number4
StatePublished - 2013
Externally publishedYes


  • Central venous catheter
  • Right atrium
  • SVC

ASJC Scopus subject areas

  • Surgery
  • Nephrology


Dive into the research topics of 'Impact of phase of respiration on central venous catheter tip position'. Together they form a unique fingerprint.

Cite this