Impact of comorbid chronic conditions to quality of life among elderly patients with diabetes mellitus in Vietnam

Huong van Nguyen, Tung Thanh Tran, Cuong Tat Nguyen, Tung Hoang Tran, Bach Xuan Tran, Carl A. Latkin, Cyrus S.H. Ho, Roger C.M. Ho

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Type 2 diabetes mellitus (T2DM) is a major cause of disease burden in the elderly population. This study aimed to measure the quality of life (QOL) among patients with T2DM and the associations between co-morbidities and QOL. A cross-sectional study was conducted on 194 patients with T2DM. The minimal clinically important difference (MCID) scores were used to indicate the clinically meaningful differences of comorbidities on quality of life. A Tobit regression was employed to find relationships between QOL and comorbidities. The mean scores of QOL domains were 50.8 (SD = 13.2) in physical, 62.4 (SD = 11.5) in psychological, 52.3 (SD = 10.2) in social relationship, and 64.3 (SD = 10.1) in environmental. Digestive and neuropsychiatric diseases had the strongest negative associations with physical QOL of patients. Neuropsychiatric diseases also had the biggest effect on psychological and environmental QOL. Meanwhile, in the social domain, respiratory diseases had the greatest effect. In conclusion, patients with T2DM struggled to perform physical functions. In addition, comorbidities significantly reduced the QOL of T2DM patients.

Original languageEnglish (US)
Article number531
JournalInternational journal of environmental research and public health
Issue number4
StatePublished - Feb 2 2019


  • Comorbidities
  • Diabetes
  • Elderly
  • Quality of life
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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