TY - JOUR
T1 - Immunomodulators in the Treatment of Nasal Polyposis
AU - Halderman, Ashleigh A.
AU - Lane, Andrew P.
PY - 2016
Y1 - 2016
N2 - The inflammatory mechanisms that contribute to chronic rhinosinusitis with nasal polyps (CRSwNP) are complex. In the past, medical options for treating CRSwNP have been limited. Emerging classes of immunomodulators such as omalizumab, anti-leukotrienes, anti-IL-4, anti-IL-5, and recognition of the modulating effects of macrolides have shown promising results in the treatment of CRSwNP. Ultimately, large randomized controlled trials are necessary to establish the efficacy of these medications but for now, the area of medical immunomodulators remains an exciting frontier.
AB - The inflammatory mechanisms that contribute to chronic rhinosinusitis with nasal polyps (CRSwNP) are complex. In the past, medical options for treating CRSwNP have been limited. Emerging classes of immunomodulators such as omalizumab, anti-leukotrienes, anti-IL-4, anti-IL-5, and recognition of the modulating effects of macrolides have shown promising results in the treatment of CRSwNP. Ultimately, large randomized controlled trials are necessary to establish the efficacy of these medications but for now, the area of medical immunomodulators remains an exciting frontier.
UR - http://www.scopus.com/inward/record.url?scp=84992154191&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84992154191&partnerID=8YFLogxK
U2 - 10.1159/000445141
DO - 10.1159/000445141
M3 - Article
C2 - 27466852
AN - SCOPUS:84992154191
SN - 0065-3071
VL - 79
SP - 103
EP - 113
JO - Advances in Oto-Rhino-Laryngology
JF - Advances in Oto-Rhino-Laryngology
ER -