Abstract
Immunology offers an unprecedented opportunity for the science-driven development of therapeutics. The successes of antibodies to the immunomodulatory receptor CTLA-4 and blockade of the immunoinhibitory receptor PD-1 in cancer immunotherapy, from gene discovery to patient benefit, have created a paradigm for driving such endeavors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1129-1132 |
| Number of pages | 4 |
| Journal | Nature Immunology |
| Volume | 13 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 2012 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
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