Immunological biomarkers of postpartum obsessive-compulsive disorder

Lauren M. Osborne

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter reviews the evidence for immunological biomarkers of perinatal obsessive-compulsive disorder (OCD). Evidence for any such biomarkers is scare at this time, but considerable evidence exists concerning both immune system dysregulation in the perinatal period and possible immune connections with OCD outside the perinatal period. The chapter reviews the evidence for these two areas, including the possible roles of autoantibodies, circulating cytokines, stimulated cytokines, and alterations in leukocyte subpopulations in OCD. This evidence is then applied to future directions of research in perinatal OCD.

Original languageEnglish (US)
Title of host publicationBiomarkers of Postpartum Psychiatric Disorders
Number of pages10
ISBN (Electronic)9780128155080
StatePublished - Jan 1 2019


  • Cytokine
  • Immune system
  • Obsessive-compulsive disorder (OCD)
  • Perinatal
  • Postpartum

ASJC Scopus subject areas

  • General Psychology


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