Immunological biomarkers of postpartum depression

Lauren M. Osborne

doi:10.1016/B978-0-12-815508-0.00005-9

Immunological biomarkers of postpartum depression

Lauren M. Osborne

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter reviews the current evidence concerning immunological biomarkers of postpartum depression (PPD). It offers a comprehensive overview of early research on immune dysregulation in PPD, which focused primarily on the cross-sectional studies of peripheral cytokines. It also offers a more detailed analysis of recent efforts to provide more sophisticated analyses of immune dysregulation, including longitudinal studies of within-woman changes; studies using summary inflammation variables; and studies connecting immune dysregulation to other systems (such as the HPA axis). While no single biomarker has been identified to date, the chapter concludes by reviewing promising future directions in the search for biomarkers.

Original language	English (US)
Title of host publication	Biomarkers of Postpartum Psychiatric Disorders
Publisher	Elsevier
Pages	65-77
Number of pages	13
ISBN (Electronic)	9780128155080
DOIs	https://doi.org/10.1016/B978-0-12-815508-0.00005-9
State	Published - Jan 1 2019

Keywords

Biomarker
Cytokines
Immune
Inflammation
Postpartum depression

ASJC Scopus subject areas

General Psychology

Access to Document

10.1016/B978-0-12-815508-0.00005-9

Cite this

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AB - This chapter reviews the current evidence concerning immunological biomarkers of postpartum depression (PPD). It offers a comprehensive overview of early research on immune dysregulation in PPD, which focused primarily on the cross-sectional studies of peripheral cytokines. It also offers a more detailed analysis of recent efforts to provide more sophisticated analyses of immune dysregulation, including longitudinal studies of within-woman changes; studies using summary inflammation variables; and studies connecting immune dysregulation to other systems (such as the HPA axis). While no single biomarker has been identified to date, the chapter concludes by reviewing promising future directions in the search for biomarkers.

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Immunological biomarkers of postpartum depression

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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