Immunologic studies in Burkitt's lymphoma

John L. Ziegler; Martin H. Cohen; Richard H. Morrow; Sebastian K. Kyalwazi; Paul P. Carbone

doi:10.1002/1097-0142(197003)25:3<734::AID-CNCR2820250335>3.0.CO;2-1

Immunologic studies in Burkitt's lymphoma

John L. Ziegler, Martin H. Cohen, Richard H. Morrow, Sebastian K. Kyalwazi, Paul P. Carbone

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

An evaluation of the immune status in patients with Burkitt's lymphoma was performed. Cellular immune responses were normal in both untreated patients and in patients in remission. An impairment of primary antibody response and low IgM levels were noted in untreated patients with Burkitt's lymphoma but not in patients in remission. A defect in humoral immunity associated with the presence of acive Burkitt's lymphoma is postulated; this defect is possibly related to IgM metabolism.

Original language	English (US)
Pages (from-to)	734-739
Number of pages	6
Journal	Cancer
Volume	25
Issue number	3
DOIs	https://doi.org/10.1002/1097-0142(197003)25:3<734::AID-CNCR2820250335>3.0.CO;2-1
State	Published - Mar 1970

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(197003)25:3<734::AID-CNCR2820250335>3.0.CO;2-1

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AU - Carbone, Paul P.

PY - 1970/3

Y1 - 1970/3

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AB - An evaluation of the immune status in patients with Burkitt's lymphoma was performed. Cellular immune responses were normal in both untreated patients and in patients in remission. An impairment of primary antibody response and low IgM levels were noted in untreated patients with Burkitt's lymphoma but not in patients in remission. A defect in humoral immunity associated with the presence of acive Burkitt's lymphoma is postulated; this defect is possibly related to IgM metabolism.

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Immunologic studies in Burkitt's lymphoma

Abstract

ASJC Scopus subject areas

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