Imatinib and beyond in gastrointestinal stromal tumors: A radiologist's perspective

Sree Harsha Tirumani; Jyothi P. Jagannathan; Katherine M. Krajewski; Atul B. Shinagare; Heather Jacene; Nikhil H. Ramaiya

doi:10.2214/AJR.12.10003

Imatinib and beyond in gastrointestinal stromal tumors: A radiologist's perspective

Sree Harsha Tirumani, Jyothi P. Jagannathan, Katherine M. Krajewski, Atul B. Shinagare, Heather Jacene, Nikhil H. Ramaiya

School of Medicine

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

OBJECTIVE. The purpose of this article is to review the decade-long experience with imatinib and other molecular targeted agents in the treatment of gastrointestinal stromal tumor (GIST). CONCLUSION. Tremendous progress has been made in the medical management of GIST since the inception of imatinib, and imaging has played a key role in understanding the typical and atypical responses of GIST to molecular targeted therapies.

Original language	English (US)
Pages (from-to)	801-810
Number of pages	10
Journal	American Journal of Roentgenology
Volume	201
Issue number	4
DOIs	https://doi.org/10.2214/AJR.12.10003
State	Published - Oct 1 2013

Keywords

CT
Gastrointestinal stromal tumor
Imatinib
PET/CT

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.2214/AJR.12.10003

Cite this

@article{c048545770754b4eaa4aa0be44042dea,

title = "Imatinib and beyond in gastrointestinal stromal tumors: A radiologist's perspective",

abstract = "OBJECTIVE. The purpose of this article is to review the decade-long experience with imatinib and other molecular targeted agents in the treatment of gastrointestinal stromal tumor (GIST). CONCLUSION. Tremendous progress has been made in the medical management of GIST since the inception of imatinib, and imaging has played a key role in understanding the typical and atypical responses of GIST to molecular targeted therapies.",

keywords = "CT, Gastrointestinal stromal tumor, Imatinib, PET/CT",

author = "Tirumani, {Sree Harsha} and Jagannathan, {Jyothi P.} and Krajewski, {Katherine M.} and Shinagare, {Atul B.} and Heather Jacene and Ramaiya, {Nikhil H.}",

year = "2013",

month = oct,

day = "1",

doi = "10.2214/AJR.12.10003",

language = "English (US)",

volume = "201",

pages = "801--810",

journal = "American Journal of Roentgenology",

issn = "0361-803X",

publisher = "American Roentgen Ray Society",

number = "4",

}

TY - JOUR

T1 - Imatinib and beyond in gastrointestinal stromal tumors

T2 - A radiologist's perspective

AU - Tirumani, Sree Harsha

AU - Jagannathan, Jyothi P.

AU - Krajewski, Katherine M.

AU - Shinagare, Atul B.

AU - Jacene, Heather

AU - Ramaiya, Nikhil H.

PY - 2013/10/1

Y1 - 2013/10/1

N2 - OBJECTIVE. The purpose of this article is to review the decade-long experience with imatinib and other molecular targeted agents in the treatment of gastrointestinal stromal tumor (GIST). CONCLUSION. Tremendous progress has been made in the medical management of GIST since the inception of imatinib, and imaging has played a key role in understanding the typical and atypical responses of GIST to molecular targeted therapies.

AB - OBJECTIVE. The purpose of this article is to review the decade-long experience with imatinib and other molecular targeted agents in the treatment of gastrointestinal stromal tumor (GIST). CONCLUSION. Tremendous progress has been made in the medical management of GIST since the inception of imatinib, and imaging has played a key role in understanding the typical and atypical responses of GIST to molecular targeted therapies.

KW - CT

KW - Gastrointestinal stromal tumor

KW - Imatinib

KW - PET/CT

UR - http://www.scopus.com/inward/record.url?scp=84886436665&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886436665&partnerID=8YFLogxK

U2 - 10.2214/AJR.12.10003

DO - 10.2214/AJR.12.10003

M3 - Review article

C2 - 24059369

AN - SCOPUS:84886436665

SN - 0361-803X

VL - 201

SP - 801

EP - 810

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 4

ER -

Imatinib and beyond in gastrointestinal stromal tumors: A radiologist's perspective

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this