Imatinib and beyond in gastrointestinal stromal tumors: A radiologist's perspective

Sree Harsha Tirumani, Jyothi P. Jagannathan, Katherine M. Krajewski, Atul B. Shinagare, Heather Jacene, Nikhil H. Ramaiya

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


OBJECTIVE. The purpose of this article is to review the decade-long experience with imatinib and other molecular targeted agents in the treatment of gastrointestinal stromal tumor (GIST). CONCLUSION. Tremendous progress has been made in the medical management of GIST since the inception of imatinib, and imaging has played a key role in understanding the typical and atypical responses of GIST to molecular targeted therapies.

Original languageEnglish (US)
Pages (from-to)801-810
Number of pages10
JournalAmerican Journal of Roentgenology
Issue number4
StatePublished - Oct 1 2013


  • CT
  • Gastrointestinal stromal tumor
  • Imatinib
  • PET/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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