Abstract
Purpose: To describe IgG4-positive sclerosing orbital inflammation with prominent conjunctival and scleral involvement. Design: Case report. Methods: Clinical, radiologic, and pathologic correlation. Results: A 66-year-old man presented with right eye redness and irritation. Examination revealed unilateral scleritis and nongranulomatous anterior uveitis with elevated p-ANCA and CRP. Orbital CT scan showed inferotemporal scleral thickening. Biopsy revealed sclerosis and IgG4-positive plasma cells in the conjunctiva and inferior rectus. Conclusions: IgG4-mediated sclerosing inflammation is well-recognized in the orbit and adnexa, particularly the lacrimal gland. Scleritis with anterior uveitis should be recognized as a possible presentation for this entity, which has important systemic associations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 375-377 |
| Number of pages | 3 |
| Journal | Ocular Immunology and Inflammation |
| Volume | 20 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2012 |
| Externally published | Yes |
Keywords
- Conjunctiva
- IgG4-positive
- Nonspecific orbital inflammation (NSOI)
- Orbital pseudotumor
- Sclerosing orbital inflammation
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology
Fingerprint
Dive into the research topics of 'IgG4-positive sclerosing orbital inflammation involving the conjunctiva: A case report'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS